Monroe was born in June 1992 in Detroit, a city in the state of Michigan. In high school, she was a cheerleader and softball player. When she turned 18, she began working as a dental assistant in a clinic. Shortly after, she left work to become a stripper and webcam girl at a Detroit club. There she met the porn actress Lexi Belle, who encouraged her to move to California and try her luck in the industry. In 2012, at the age of 20, Zoey Monroe made her debut as a porn actress under her current stage name. She has worked in films for production companies such as Evil Angel, Jules Jordan Video, Hard X, Girlfriends Films, 3rd Degree, Hustler, Adam & Eve, Kick-Ass, Girlsway, Lethal Hardcore, Smash Pictures, Immoral Productions, Pulse Distribution or Pure Play Media. In addition, she has appeared on various web portals such as Brazzers, Bang Bros, Reality Kings, or Naughty America. In 2014, she received her first AVN Award nominations in the category of Best New Actress and Best M-H-M Threesome Scene for Weapons of Ass Destruction 76 alongside Gabriella Paltrova and James Deen. That same year she won the award for Best Transsexual Sex Scene for Rogue Adventures 38. Evil Angel film directed by Joey Silvera and starring transsexual actress Jacqueline Woods, Monroe's award partner. In 2015 she returned to the AVN with four other nominations, 8 highlighting those for Female Artist of the Year, Best Double Penetration Scene for Wet Asses 4. with James Deen and Ramón Nomar, and Best Scandalous Sex Scene for Cream Dreams 2.10 nominated alongside Anikka Albrite. In 2016 she returned with another nomination for Best Group Lesbian Sex Scene for the film Angels and Devils alongside Natasha Voya and Keira Nicole. She has shot more than 460 films as an actress. Some of his filmography titles are Ass Hysteria, Blowjob Auditions 3, DP Me, His Ass Is Mine, Resurrection, I Wanna Buttfuck Your Daughter 16, My Dad's Hot Wife, Prison Lesbians 3 O Young Freaks 4